Cambodia Travel Vaccines — What You Need in 2026

Recommended Vaccines

• Hepatitis A

  Allow 2 weeks before travel

• Typhoid

  Allow 2 weeks before travel

• Rabies

  Allow 4 weeks before travel

• Japanese Encephalitis

  Allow 4 weeks before travel

Routine Vaccines to Keep Up to Date

Other Health Risks

• Dengue
• Malaria (rural border regions)

Travel Health Summary

Cambodia's risk profile depends heavily on whether you stay on the temple-and-city circuit or head into the forests. Phnom Penh and Siem Reap including the Angkor complex are considered malaria-free, while transmission continues in forested and border areas, particularly Ratanakiri, Mondulkiri, Preah Vihear and the Thai and Laotian border zones, where antimalarial tablets are recommended for overnight stays; this region also has documented artemisinin resistance, so the choice of drug should be made by a travel clinic rather than assumed. Dengue is endemic nationwide with a strong wet-season peak from roughly June to October and regularly causes large urban outbreaks, so repellent and screened or air-conditioned accommodation matter everywhere. Hepatitis A and typhoid are recommended for nearly all travellers, since tap water is unsafe, ice and raw vegetables are common sources of illness, and street food is a central part of most itineraries. Japanese encephalitis vaccination is advised for longer stays and rural, rice-growing areas, and rabies is a serious concern: Cambodia has one of the highest per-capita rabies death rates in the world, monkeys around the Angkor temples bite tourists regularly, and post-exposure immunoglobulin is only reliably available at the Institut Pasteur in Phnom Penh, which makes pre-exposure vaccination a strong recommendation. Road traffic injury and motorbike accidents account for more serious traveller harm than any infection. Royal Phnom Penh Hospital and the Royal Angkor International Hospital in Siem Reap handle routine cases, but serious trauma and critical care are usually evacuated to Bangkok, so insurance with evacuation cover is essential.

Related destinations

Nearby countries with a comparable vaccine and disease-risk profile to Cambodia.